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tirabrutinib MeSH Supplementary Concept Data 2023


MeSH Supplementary
tirabrutinib
Unique ID
C000608238
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C000608238
Entry Term(s)
6-Amino-9-((3R)-1-(2-butynoyl)-3-pyrrolidinyl)-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purin-8-one
8H-Purin-8-one, 6-amino-7,9-dihydro-9-((3R)-1-(1-oxo-2-butyn-1-yl)-3-pyrrolidinyl)-7-(4-phenoxyphenyl)-
GS-4059
ONO-4059
Registry Number
LXG44NDL2T
Heading Mapped to
*Imidazoles
*Pyrimidines
Frequency
40
Note
a Bruton tyrosine kinase with antineoplastic activity; in phase I clinical trials (2016); structure in first source
Source
Blood. 2016 Jan 28;127(4):411-9.
Date of Entry
2016/06/12
Revision Date
2020/09/14
tirabrutinib Preferred
6-Amino-9-((3R)-1-(2-butynoyl)-3-pyrrolidinyl)-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purin-8-one Broader
GS-4059 Narrower
ONO-4059 Narrower
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