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Pegloticase MeSH Supplementary Concept Data 2023


MeSH Supplementary
Pegloticase
Unique ID
C031545
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C031545
Entry Term(s)
Krystexxa
PEG-uricase
Puricase
methoxypolyethylene glycol uricase
polyethylene glycol-uricase
Registry Number
R581OT55EA
Heading Mapped to
*Polyethylene Glycols
*Urate Oxidase
Frequency
104
Note
uricase covalently attached to polyethylene glycol, modifying 71% of amino groups & retaining 11% of activity without eliciting antibody response in mice or man; used for lowering serum uric acid
Source
Lancet 1981;2(8241):281
Indexing Information
Enzymes, Immobilized
Date of Entry
1981/09/11
Revision Date
2017/07/25
Pegloticase Preferred
Krystexxa Narrower
Puricase Narrower
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