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2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-2-hepten-6-ynamide MeSH Supplementary Concept Data 2023


MeSH Supplementary
2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-2-hepten-6-ynamide
Unique ID
C115284
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C115284
Entry Term(s)
2-cyano-3-hydroxy-N-(4--(trifluoromethyl)phenyl)-2-hepten-6-ynoic acid
FK 778
FK-778
FK778
HMR 1715
HMR-1715
MNA 715
MNA-715
MNA-X 920715
X 920715
X-920715
malononitrilamide 715
malononitrilamide-715
Registry Number
185915-33-7
Related Numbers
4B135RK2KL
Heading Mapped to
*Alkynes
*Isoxazoles
*Nitriles
Frequency
104
Note
structure in first source; a derivative of A77 1726, the active metabolite of the antirheumatic drug leflunomide, where the isoxazole ring has opened to become a nitrile and an alkyne
Source
Rapid Commun Mass Spectrom. 2005;19(18):2681-8
Scand J Immunol 1998 Oct;48(4):379-88
Date of Entry
1998/11/12
Revision Date
2018/11/16
2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-2-hepten-6-ynamide Preferred
FK778 Narrower
X 920715 Narrower
malononitrilamide 715 Narrower
MNA 715 Related
MNA-X 920715 Narrower
2-cyano-3-hydroxy-N-(4--(trifluoromethyl)phenyl)-2-hepten-6-ynoic acid Related
HMR 1715 Narrower
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