MeSH Browser

MeSH Supplementary: Anonychia congenita
Unique ID: C536377
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C536377
Entry Term(s): Anonychia; Hyponychia congenita
Registry Number: 0
Heading Mapped to: Nails, Malformed / *congenital
Frequency: 27
Note: The absence of fingernails and toenails (anonychia) and its milder phenotypic variant (hyponychia), are usually associated with other skeletal and limb abnormalities in genetic syndromes. Isolated nonsyndromic cases are less common and may show autosomal recessive inheritance and variable expression within a given family. The nail phenotypes can vary from no nail field to a nail field of reduced size with an absent or rudimentary nail. Nonsyndromic cases are associated with mutations in the R-spondin 4 (RSPO4) gene. OMIM: 610573
Date of Entry: 2010/11/13
Revision Date: 2016/09/29

Anonychia congenita MeSH Supplementary Concept Data 2023