MeSH Browser

MeSH Supplementary: Neurocutaneous melanosis
Unique ID: C537387
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C537387
Entry Term(s): Melanosis, neurocutaneous; Neurocutaneous melanosis syndrome
Registry Number: 0
Heading Mapped to: *Melanosis; *Neurocutaneous Syndromes
Frequency: 95
Note: A disorder characterized by the presence of melanin-producing cells within the brain parenchyma or leptomeninges, which may cause neurologic signs and symptoms, such as SEIZURES; HYDROCEPHALUS; ARACHNOID CYSTS; BRAIN NEOPLASMS, and SYRINGOMYELIA. Occurs as a rare but severe manifestation of congenital MELANOCYTIC NEVUS syndrome (CMNS) (OMIM: 137550). Some patients with neurocutaneous melanosis or CMNS may develop MELANOMA. Somatic mutations in the NRAS gene have been identified. OMIM: 249400
Date of Entry: 2010/08/25
Revision Date: 2015/08/18

Neurocutaneous melanosis MeSH Supplementary Concept Data 2023