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2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid
MeSH Supplementary Concept Data 2022
Details
Concepts
MeSH Supplementary
2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid
Unique ID
C588087
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C588087
Entry Term(s)
AMG 232
Registry Number
0
Heading Mapped to
*Acetates
*Piperidones
Frequency
12
Note
inhibits the interaction between p53 and MDM2; structure in first source
Source
J Med Chem. 2014 Feb 27;57(4):1454-72.
Indexing Information
Antineoplastic Agents
Date of Entry
2014/04/27
Revision Date
2014/04/27
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2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid
Preferred
Concept UI
M0593898
Registry Number
0
Terms
2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid
Preferred Term
Term UI
T859114
Date
04/27/2014
LexicalTag
NON
ThesaurusID
NLM (2014)
AMG 232
Narrower
Concept UI
M0593899
Terms
AMG 232
Preferred Term
Term UI
T859115
Date
04/27/2014
LexicalTag
LAB
ThesaurusID
NLM (2014)
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