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2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid MeSH Supplementary Concept Data 2023


MeSH Supplementary
2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid
Unique ID
C588087
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C588087
Entry Term(s)
AMG 232
Registry Number
0
Heading Mapped to
*Acetates
*Piperidones
Frequency
11
Note
inhibits the interaction between p53 and MDM2; structure in first source
Source
J Med Chem. 2014 Feb 27;57(4):1454-72.
Indexing Information
Antineoplastic Agents
Date of Entry
2014/04/27
Revision Date
2014/04/27
2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid Preferred
AMG 232 Narrower
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