MeSH Browser

MeSH Heading: Histiocytosis, Langerhans-Cell
Tree Number(s): C08.381.483.375; C15.604.250.400
Unique ID: D006646
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D006646
Scope Note: A group of disorders resulting from the abnormal proliferation of and tissue infiltration by LANGERHANS CELLS which can be detected by their characteristic Birbeck granules (X bodies), or by monoclonal antibody staining for their surface CD1 ANTIGENS. Langerhans-cell granulomatosis can involve a single organ, or can be a systemic disorder.
Entry Term(s): Hand-Schueller-Christian Disease; Hand-Schueller-Christian Syndrome; Hand-Schüller-Christian Disease; Hand-Schüller-Christian Syndrome; Hashimoto-Pritzger Disease; Histiocytosis X; Histiocytosis, Generalized; Histiocytosis-X; Langerhans Cell Granulomatosis; Langerhans Cell Granulomatosis, Pulmonary; Langerhans Cell Histiocytosis; Langerhans-Cell Granulomatosis; Langerhans-Cell Histiocytosis; Letterer-Siwe Disease; Non-Lipid Reticuloendotheliosis; Pulmonary Histiocytosis X; Pulmonary Langerhans Cell Granulomatosis; Schueller-Christian Disease; Systemic Aleukemic Reticuloendotheliosis; Type 2 Histiocytosis
NLM Classification #: WH 720
Previous Indexing: Reticuloendotheliosis (1966-1974)
Public MeSH Note: 90; was see under RETICULOENDOTHELIOSIS 1965-75; was HISTIOCYTOSIS X 1975-89
Online Note: use HISTIOCYTOSIS, LANGERHANS-CELL to search HISTIOCYTOSIS X 1975-89; use RETICULOENDOTHELIOSIS 1966-74
History Note: 90(75); was see under RETICULOENDOTHELIOSIS 1966-75; was HISTIOCYTOSIS X 1975-89
Date Established: 1976/01/01
Date of Entry: 1975/07/25
Revision Date: 2023/05/31

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

congenital (CN)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Respiratory Tract Diseases [C08]
- Lung Diseases [C08.381]
  - Lung Diseases, Interstitial [C08.381.483]

Hemic and Lymphatic Diseases [C15]
- Lymphatic Diseases [C15.604]
  - Histiocytosis [C15.604.250]

Histiocytosis, Langerhans-Cell Preferred

Concept UI: M0010406
Scope Note: A group of disorders resulting from the abnormal proliferation of and tissue infiltration by LANGERHANS CELLS which can be detected by their characteristic Birbeck granules (X bodies), or by monoclonal antibody staining for their surface CD1 ANTIGENS. Langerhans-cell granulomatosis can involve a single organ, or can be a systemic disorder.
Terms: Histiocytosis, Langerhans-Cell Preferred Term
Term UI T020013
Date01/01/1999
LexicalTag EPO
ThesaurusID NLM (1976); Histiocytosis X
Term UI T020012
Date01/18/1989
LexicalTag NON
ThesaurusID; Histiocytosis, Generalized
Term UI T023615
Date01/19/1989
LexicalTag NON
ThesaurusID NLM (1990); Histiocytosis-X
Term UI T020011
Date07/11/1975
LexicalTag NON
ThesaurusID UNK (19XX); Langerhans Cell Histiocytosis
Term UI T811619
Date11/15/2011
LexicalTag NON
ThesaurusID; Langerhans-Cell Granulomatosis
Term UI T020014
Date01/18/1989
LexicalTag EPO
ThesaurusID; Langerhans-Cell Histiocytosis
Term UI T705960
Date09/18/2007
LexicalTag EPO
ThesaurusID; Non-Lipid Reticuloendotheliosis
Term UI T782967
Date12/28/2010
LexicalTag NON
ThesaurusID; Schueller-Christian Disease
Term UI T018896
Date03/30/1974
LexicalTag EPO
ThesaurusID UNK (19XX); Systemic Aleukemic Reticuloendotheliosis
Term UI T782968
Date12/28/2010
LexicalTag NON
ThesaurusID; Type 2 Histiocytosis
Term UI T782969
Date12/28/2010
LexicalTag NON
ThesaurusID; Langerhans Cell Granulomatosis
Term UI T841871
Date04/18/2013
LexicalTag NON
ThesaurusID GHR (2014)

Pulmonary Histiocytosis X Narrower

Hashimoto-Pritzger Disease Narrower

Hand-Schueller-Christian Syndrome Broader

Letterer-Siwe Disease Narrower

Histiocytosis, Langerhans-Cell MeSH Descriptor Data 2024