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Langerhans Cells MeSH Descriptor Data 2023


MeSH Heading
Langerhans Cells
Tree Number(s)
A11.066.270.500
A11.436.270.545
A15.382.066.270.500
A15.382.670.260.500
Unique ID
D007801
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D007801
Annotation
cutaneous cells: do not confuse with ISLETS OF LANGERHANS (pancreas) nor with GIANT CELLS, LANGHANS (macrophages)
Scope Note
Recirculating, dendritic, antigen-presenting cells containing characteristic racket-shaped granules (Birbeck granules). They are found principally in the stratum spinosum of the EPIDERMIS and are rich in Class II MAJOR HISTOCOMPATIBILITY COMPLEX molecules. Langerhans cells were the first dendritic cell to be described and have been a model of study for other dendritic cells (DCs), especially other migrating DCs such as dermal DCs and INTERSTITIAL DENDRITIC CELLS.
Entry Term(s)
Dendritic Cells, Dermal
Dendritic Cells, Epidermal
Dendritic Cells, Skin
Dermal Dendritic Cells
Epidermal Dendritic Cells
Langerhans Cell
Skin Dendritic Cells
Previous Indexing
Cytoplasmic Granules (1966-1968)
Epithelium (1966-1968)
Skin (1966-1968)
Public MeSH Note
73
History Note
73(69)
Date Established
1973/01/01
Date of Entry
1999/01/01
Revision Date
2020/05/27
Langerhans Cells Preferred
Skin Dendritic Cells Broader
Dermal Dendritic Cells Related
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