MeSH Browser

MeSH Heading: Antigen-Presenting Cells
Tree Number(s): A11.066; A15.382.066
Unique ID: D000938
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000938
Scope Note: A heterogeneous group of immunocompetent cells that mediate the cellular immune response by processing and presenting antigens to the T-cells. Traditional antigen-presenting cells include MACROPHAGES; DENDRITIC CELLS; LANGERHANS CELLS; and B-LYMPHOCYTES. FOLLICULAR DENDRITIC CELLS are not traditional antigen-presenting cells, but because they hold antigen on their cell surface in the form of IMMUNE COMPLEXES for B-cell recognition they are considered so by some authors.
Entry Term(s): Accessory Cell, Immunologic; Accessory Cells, Immunologic; Antigen-Presenting Cell; Cell, Immunologic Accessory; Cells, Immunologic Accessory; Immunologic Accessory Cell; Immunologic Accessory Cells
NLM Classification #: QW 568
Previous Indexing: Antigenic Determinants (1970-1984); Antigens, Immune Response (1981-1984); Lymphocyte Transformation (1969-1984); T Lymphocytes (1973-1984)
See Also: Antigen Presentation; Histocompatibility Antigens Class II; Lymphocyte Activation
Public MeSH Note: 85
History Note: 85
Date Established: 1985/01/01
Date of Entry: 1984/05/30
Revision Date: 2020/05/27

Allowable Qualifiers: chemistry (CH)

classification (CL)

cytology (CY)

drug effects (DE)

enzymology (EN)

immunology (IM)

metabolism (ME)

microbiology (MI)

parasitology (PS)

pathology (PA)

physiology (PH)

radiation effects (RE)

transplantation (TR)

ultrastructure (UL)

virology (VI)

Concept UI: M0001402
Scope Note: A heterogeneous group of immunocompetent cells that mediate the cellular immune response by processing and presenting antigens to the T-cells. Traditional antigen-presenting cells include MACROPHAGES; DENDRITIC CELLS; LANGERHANS CELLS; and B-LYMPHOCYTES. FOLLICULAR DENDRITIC CELLS are not traditional antigen-presenting cells, but because they hold antigen on their cell surface in the form of IMMUNE COMPLEXES for B-cell recognition they are considered so by some authors.
Terms: Antigen-Presenting Cells Preferred Term
Term UI T002795
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1985); Accessory Cell, Immunologic
Term UI T002796
Date08/25/1992
LexicalTag NON
ThesaurusID NLM (1994); Accessory Cells, Immunologic
Term UI T002800
Date05/30/1984
LexicalTag NON
ThesaurusID UNK (19XX); Cell, Immunologic Accessory
Term UI T002797
Date08/25/1992
LexicalTag NON
ThesaurusID NLM (1994); Cells, Immunologic Accessory
Term UI T002798
Date05/30/1984
LexicalTag NON
ThesaurusID UNK (19XX); Immunologic Accessory Cell
Term UI T002799
Date10/09/1997
LexicalTag NON
ThesaurusID NLM (1999); Antigen-Presenting Cell
Term UI T001006475
Date01/29/2020
LexicalTag NON
ThesaurusID NLM (2021); Immunologic Accessory Cells
Term UI T002801
Date12/13/1989
LexicalTag NON
ThesaurusID NLM (1991)

Antigen-Presenting Cells MeSH Descriptor Data 2025