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trilostane MeSH Supplementary Concept Data 2023


MeSH Supplementary
trilostane
Unique ID
C009954
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C009954
Entry Term(s)
4alpha,5-epoxy-17beta-hydroxy-3-oxoandrostane-2-carbonitrile
Modrenal
WIN 24,540
Pharm Action
Abortifacient Agents, Steroidal
Antineoplastic Agents
Enzyme Inhibitors
Registry Number
L0FPV48Q5R
Related Numbers
13647-35-3
Previous Indexing
*ANDROSTANES (75-80)
*ANDROSTANOLS (80-82)
NITRILES (75-82)
Heading Mapped to
Dihydrotestosterone / *analogs & derivatives
Frequency
321
Note
inhibits conversion of pregnenolone to progesterone; adrenal blocking agent used in treatment of Cushing's syndrome
Source
Endocrinology 103(4):1411;1978
Endocrinology 97(1):136;1975
Fertil Steril 1979;32(4):464
J Endocrinol 76:293;1978
Steroids 32(2):257;1978
Indexing Information
Oxidative Phosphorylation Coupling Factors
3-Hydroxysteroid Dehydrogenases
Date of Entry
1975/01/01
Revision Date
2015/09/27
trilostane Preferred
Modrenal Narrower
WIN 24,540 Narrower
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