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Enzyme Inhibitors
MeSH Descriptor Data 2024
Details
Qualifiers
MeSH Tree Structures
Concepts
MeSH Heading
Enzyme Inhibitors
Tree Number(s)
D27.505.519.389
Unique ID
D004791
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D004791
Annotation
general or unspecified; prefer specifics
Scope Note
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
Entry Version
ENZYME INHIB
Entry Term(s)
Enzyme Inhibitor
Registry Numbers
0
NLM Classification #
QU 143
Previous Indexing
Enzymes (1966-1967)
Enzymes/antagonists & inhibitors (1968-1974)
Public MeSH Note
1975, 1964-1967
History Note
1975(1964)
Date Established
1975/09/01
Date of Entry
1999/01/01
Revision Date
2021/03/04
Allowable Qualifiers
administration & dosage (AD)
adverse effects (AE)
analysis (AN)
blood (BL)
cerebrospinal fluid (CF)
chemical synthesis (CS)
chemistry (CH)
classification (CL)
economics (EC)
history (HI)
immunology (IM)
isolation & purification (IP)
metabolism (ME)
pharmacokinetics (PK)
pharmacology (PD)
poisoning (PO)
radiation effects (RE)
standards (ST)
supply & distribution (SD)
therapeutic use (TU)
toxicity (TO)
urine (UR)
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Molecular Mechanisms of Pharmacological Action [D27.505.519]
Alkylating Agents [D27.505.519.124]
Amylin Receptor Agonists [D27.505.519.143]
Angiotensin Receptor Antagonists [D27.505.519.162]
Antacids [D27.505.519.170]
Antidiuretic Hormone Receptor Antagonists [D27.505.519.174]
Antifoaming Agents [D27.505.519.178]
Antiglycation Agents [D27.505.519.182]
Antimetabolites [D27.505.519.186]
Antioxidants [D27.505.519.217]
Aversive Agents [D27.505.519.241]
Bradykinin Receptor Antagonists [D27.505.519.265]
Calcitonin Gene-Related Peptide Receptor Antagonists [D27.505.519.270]
CCR5 Receptor Antagonists [D27.505.519.275]
Cerumenolytic Agents [D27.505.519.295]
Cystine Depleting Agents [D27.505.519.334]
Cytochrome P-450 Enzyme Inducers [D27.505.519.349]
Endothelin Receptor Antagonists [D27.505.519.364]
Enzyme Activators [D27.505.519.374]
Enzyme Inhibitors [D27.505.519.389]
5-Lipoxygenase-Activating Protein Inhibitors [D27.505.519.389.086]
Acetaldehyde Dehydrogenase Inhibitors [D27.505.519.389.089]
Adenosine Deaminase Inhibitors [D27.505.519.389.092]
Adenylyl Cyclase Inhibitors [D27.505.519.389.108]
Aromatic Amino Acid Decarboxylase Inhibitors [D27.505.519.389.124]
Calcineurin Inhibitors [D27.505.519.389.174]
Carbonic Anhydrase Inhibitors [D27.505.519.389.200]
Catechol O-Methyltransferase Inhibitors [D27.505.519.389.237]
Cholinesterase Inhibitors [D27.505.519.389.275]
Cyclooxygenase Inhibitors [D27.505.519.389.310]
Gamma Secretase Inhibitors and Modulators [D27.505.519.389.315]
Glycoside Hydrolase Inhibitors [D27.505.519.389.320]
Cytochrome P-450 Enzyme Inhibitors [D27.505.519.389.335]
Folic Acid Antagonists [D27.505.519.389.350]
Histone Deacetylase Inhibitors [D27.505.519.389.360]
Hydroxymethylglutaryl-CoA Reductase Inhibitors [D27.505.519.389.370]
Integrase Inhibitors [D27.505.519.389.375]
beta-Lactamase Inhibitors [D27.505.519.389.400]
Lipoxygenase Inhibitors [D27.505.519.389.480]
Monoamine Oxidase Inhibitors [D27.505.519.389.616]
Nucleic Acid Synthesis Inhibitors [D27.505.519.389.675]
Ornithine Decarboxylase Inhibitors [D27.505.519.389.705]
Phosphodiesterase Inhibitors [D27.505.519.389.735]
Phosphoinositide-3 Kinase Inhibitors [D27.505.519.389.736]
Phospholipase A2 Inhibitors [D27.505.519.389.737]
Poly(ADP-ribose) Polymerase Inhibitors [D27.505.519.389.739]
Prolyl-Hydroxylase Inhibitors [D27.505.519.389.740]
Protease Inhibitors [D27.505.519.389.745]
Protein Kinase Inhibitors [D27.505.519.389.755]
Protein Synthesis Inhibitors [D27.505.519.389.760]
Proton Pump Inhibitors [D27.505.519.389.848]
Steroid Synthesis Inhibitors [D27.505.519.389.870]
Topoisomerase Inhibitors [D27.505.519.389.892]
Uncoupling Agents [D27.505.519.389.936]
Enzyme Reactivators [D27.505.519.405]
Fibrin Modulating Agents [D27.505.519.421]
Heparin Antagonists [D27.505.519.452]
Immune Checkpoint Inhibitors [D27.505.519.507]
Membrane Transport Modulators [D27.505.519.562]
Mitosis Modulators [D27.505.519.593]
Neurotransmitter Agents [D27.505.519.625]
Nitric Oxide Donors [D27.505.519.656]
Peptidomimetics [D27.505.519.828]
Radiopharmaceuticals [D27.505.519.871]
Sequestering Agents [D27.505.519.914]
Sodium-Glucose Transporter 2 Inhibitors [D27.505.519.936]
Sphingosine 1 Phosphate Receptor Modulators [D27.505.519.947]
Toll-Like Receptor Agonists [D27.505.519.952]
Viral Fusion Protein Inhibitors [D27.505.519.957]
Expand All
Collapse All
Enzyme Inhibitors
Preferred
Concept UI
M0007520
Registry Numbers
0
Scope Note
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
Terms
Enzyme Inhibitors
Preferred Term
Term UI
T014636
Date
01/01/1999
LexicalTag
NON
ThesaurusID
POPLINE (1978)
Enzyme Inhibitor
Term UI
T000996333
Date
11/14/2019
LexicalTag
NON
ThesaurusID
NLM (2021)
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