MeSH Browser

MeSH Heading: Protease Inhibitors
Tree Number(s): D27.505.519.389.745
Unique ID: D011480
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D011480
Annotation: PROTEASE INHIBITORY PROTEINS, SECRETORY is also available
Scope Note: Compounds which inhibit or antagonize biosynthesis or actions of proteases (ENDOPEPTIDASES).
Entry Version: PROTEASE INHIB
Entry Term(s): Antiprotease; Antiproteases; Endopeptidase Inhibitor; Endopeptidase Inhibitors; Peptidase Inhibitor; Peptidase Inhibitors; Peptide Hydrolase Inhibitor; Peptide Hydrolase Inhibitors; Peptide Peptidohydrolase Inhibitor; Peptide Peptidohydrolase Inhibitors; Protease Antagonist; Protease Antagonists; Protease Inhibitor
NLM Classification #: QU 143
Previous Indexing: Peptide Hydrolases/antagonists & inhibitors (1968-1978); Peptide Peptidohydrolases/antagonists & inhibitors (1968-1978)
See Also: Proteinase Inhibitory Proteins, Secretory
Public MeSH Note: 79
History Note: 79
Date Established: 1979/01/01
Date of Entry: 1978/05/19
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Chemical Actions and Uses [D27]
- Pharmacologic Actions [D27.505]
  - Molecular Mechanisms of Pharmacological Action [D27.505.519]
    - Enzyme Inhibitors [D27.505.519.389]

Protease Inhibitors Preferred

Concept UI: M0017845
Scope Note: Compounds which inhibit or antagonize biosynthesis or actions of proteases (ENDOPEPTIDASES).
Terms: Protease Inhibitors Preferred Term
Term UI T033911
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1979); Peptide Peptidohydrolase Inhibitor
Term UI T000998348
Date11/20/2019
LexicalTag NON
ThesaurusID NLM (2021); Antiprotease
Term UI T000998344
Date11/20/2019
LexicalTag NON
ThesaurusID NLM (2021); Endopeptidase Inhibitor
Term UI T000998345
Date11/20/2019
LexicalTag NON
ThesaurusID NLM (2021); Peptidase Inhibitor
Term UI T000998346
Date11/20/2019
LexicalTag NON
ThesaurusID NLM (2021); Peptide Hydrolase Inhibitor
Term UI T000998347
Date11/20/2019
LexicalTag NON
ThesaurusID NLM (2021); Protease Antagonist
Term UI T000998349
Date11/20/2019
LexicalTag NON
ThesaurusID NLM (2021); Endopeptidase Inhibitors
Term UI T363828
Date11/04/1999
LexicalTag NON
ThesaurusID NLM (2000); Peptidase Inhibitors
Term UI T033906
Date05/19/1978
LexicalTag NON
ThesaurusID UNK (19XX); Peptide Hydrolase Inhibitors
Term UI T033907
Date05/19/1978
LexicalTag NON
ThesaurusID UNK (19XX); Peptide Peptidohydrolase Inhibitors
Term UI T033908
Date05/19/1978
LexicalTag NON
ThesaurusID UNK (19XX); Protease Antagonists
Term UI T033909
Date05/19/1978
LexicalTag NON
ThesaurusID UNK (19XX); Antiproteases
Term UI T033905
Date03/22/1989
LexicalTag NON
ThesaurusID NLM (1990); Protease Inhibitor
Term UI T033910
Date05/09/1987
LexicalTag NON
ThesaurusID UNK (19XX)

Protease Inhibitors MeSH Descriptor Data 2025