MeSH Browser

MeSH Heading: Proteinase Inhibitory Proteins, Secretory
Tree Number(s): D12.644.822; D12.776.815
Unique ID: D053491
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D053491
Scope Note: Peptides and proteins found in BODILY SECRETIONS and BODY FLUIDS that are PROTEASE INHIBITORS. They play a role in INFLAMMATION, tissue repair and innate immunity (IMMUNITY, INNATE) by inhibiting endogenous proteinases such as those produced by LEUKOCYTES and exogenous proteases such as those produced by invading microorganisms.
Entry Term(s): Neutrophil Elastase Inhibitor; Neutrophil Elastase Inhibitors; Peptidase Inhibitory Peptides, Secretory; Peptidase Inhibitory Proteins, Secretory; Protease Inhibitory Peptides, Secretory; Protease Inhibitory Proteins, Secretory; Proteinase Inhibitory Peptides, Secretory
Pharm Action: Protease Inhibitors
See Also: Protease Inhibitors
Public MeSH Note: 2007; NEUTROPHIL ELASTASE INHIBITORS was indexed under PROTEINS 1996-2006, under SERINE PROTEINASE INHIBITORS 1990-1995, under PROTEASE INHIBITORS 1980-1989, under ENZYME INHIBITORS 1978-1979, & under PEPTIDE PEPTIDOHYDROLASES 1978-1979
History Note: 2007(1980)
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2022/07/12

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Proteinase Inhibitory Proteins, Secretory MeSH Descriptor Data 2025