NLM Logo

Receptors, Cytoplasmic and Nuclear MeSH Descriptor Data 2023

MeSH Heading
Receptors, Cytoplasmic and Nuclear
Tree Number(s)
Unique ID
RDF Unique Identifier
general or unspecified; prefer specifics; for hormone receptors, see note at RECEPTORS, CELL SURFACE
Scope Note
Intracellular receptors that can be found in the cytoplasm or in the nucleus. They bind to extracellular signaling molecules that migrate through or are transported across the CELL MEMBRANE. Many members of this class of receptors occur in the cytoplasm and are transported to the CELL NUCLEUS upon ligand-binding where they signal via DNA-binding and transcription regulation. Also included in this category are receptors found on INTRACELLULAR MEMBRANES that act via mechanisms similar to CELL SURFACE RECEPTORS.
Entry Version
Entry Term(s)
Cytoplasmic Hormone Receptors
Cytoplasmic Receptor
Cytoplasmic Receptors
Cytoplasmic and Nuclear Receptors
Cytosol and Nuclear Receptors
Cytosolic and Nuclear Receptors
Hormone Receptors, Cytoplasmic
Hormone Receptors, Nuclear
Intracellular Membrane Receptors
Nuclear Hormone Receptor
Nuclear Hormone Receptors
Nuclear Receptor
Nuclear Receptors
Nuclear and Cytoplasmic Receptors
Receptors, Cytoplasmic
Receptors, Cytosol and Nuclear
Receptors, Cytosolic and Nuclear
Receptors, Intracellular Membrane
Receptors, Nuclear
Receptors, Nuclear and Cytoplasmic
Registry Number
NLM Classification #
QU 55.2
Previous Indexing
Receptors, Cell Surface (1983-1993)
Public MeSH Note
History Note
Date Established
Date of Entry
Revision Date
Receptors, Cytoplasmic and Nuclear Preferred
Receptors, Nuclear Narrower
Receptors, Cytoplasmic Narrower
Receptors, Intracellular Membrane Narrower
Hormone Receptors, Cytoplasmic Narrower
Hormone Receptors, Nuclear Narrower
page delivered in 0.293s