MeSH Browser

MeSH Heading: Receptors, Cytoplasmic and Nuclear
Tree Number(s): D12.776.826
Unique ID: D018160
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D018160
Annotation: general or unspecified; prefer specifics; for hormone receptors, see note at RECEPTORS, CELL SURFACE
Scope Note: Intracellular receptors that can be found in the cytoplasm or in the nucleus. They bind to extracellular signaling molecules that migrate through or are transported across the CELL MEMBRANE. Many members of this class of receptors occur in the cytoplasm and are transported to the CELL NUCLEUS upon ligand-binding where they signal via DNA-binding and transcription regulation. Also included in this category are receptors found on INTRACELLULAR MEMBRANES that act via mechanisms similar to CELL SURFACE RECEPTORS.
Entry Version: RECEPT CYTOPLASMIC NUCLEAR
Entry Term(s): Cytoplasmic Hormone Receptors; Cytoplasmic Receptor; Cytoplasmic Receptors; Cytoplasmic and Nuclear Receptors; Cytosol and Nuclear Receptors; Cytosolic and Nuclear Receptors; Hormone Receptors, Cytoplasmic; Hormone Receptors, Nuclear; Intracellular Membrane Receptors; Nuclear Hormone Receptor; Nuclear Hormone Receptors; Nuclear Receptor; Nuclear Receptors; Nuclear and Cytoplasmic Receptors; Receptors, Cytoplasmic; Receptors, Cytosol and Nuclear; Receptors, Cytosolic and Nuclear; Receptors, Intracellular Membrane; Receptors, Nuclear; Receptors, Nuclear and Cytoplasmic
NLM Classification #: QU 55.2
Previous Indexing: Receptors, Cell Surface (1983-1993)
Public MeSH Note: 94
History Note: 94
Date Established: 1994/01/01
Date of Entry: 1993/06/30
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]

Receptors, Cytoplasmic and Nuclear Preferred

Concept UI: M0027373
Scope Note: Intracellular receptors that can be found in the cytoplasm or in the nucleus. They bind to extracellular signaling molecules that migrate through or are transported across the CELL MEMBRANE. Many members of this class of receptors occur in the cytoplasm and are transported to the CELL NUCLEUS upon ligand-binding where they signal via DNA-binding and transcription regulation. Also included in this category are receptors found on INTRACELLULAR MEMBRANES that act via mechanisms similar to CELL SURFACE RECEPTORS.
Terms: Receptors, Cytoplasmic and Nuclear Preferred Term
Term UI T054344
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1994); Nuclear and Cytoplasmic Receptors
Term UI T054343
Date04/15/1993
LexicalTag NON
ThesaurusID NLM (1994); Receptors, Cytosol and Nuclear
Term UI T054338
Date04/15/1993
LexicalTag NON
ThesaurusID NLM (1994); Receptors, Cytosolic and Nuclear
Term UI T054339
Date04/15/1993
LexicalTag NON
ThesaurusID NLM (1994); Receptors, Nuclear and Cytoplasmic
Term UI T054341
Date04/15/1993
LexicalTag NON
ThesaurusID NLM (1994); Cytoplasmic and Nuclear Receptors
Term UI T054342
Date03/10/1993
LexicalTag NON
ThesaurusID NLM (1994); Cytosol and Nuclear Receptors
Term UI T054337
Date05/06/1993
LexicalTag NON
ThesaurusID NLM (1994); Cytosolic and Nuclear Receptors
Term UI T054340
Date04/15/1993
LexicalTag NON
ThesaurusID NLM (1994)

Receptors, Cytoplasmic Narrower

Receptors, Nuclear Narrower

Hormone Receptors, Nuclear Narrower

Hormone Receptors, Cytoplasmic Narrower

Receptors, Intracellular Membrane Narrower

Receptors, Cytoplasmic and Nuclear MeSH Descriptor Data 2025