MeSH Browser

MeSH Heading: Liver X Receptors
Tree Number(s): D12.776.260.531; D12.776.826.194
Unique ID: D000071518
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000071518
Scope Note: Nuclear receptors that bind OXYSTEROLS and function as heterodimers with RETINOID X RECEPTORS. They have important functions in regulating cholesterol homeostasis, ENERGY METABOLISM; INFLAMMATION; and the immune response.
Entry Term(s): LXR-Alpha Protein; LXRalpha Protein; LXRbeta Protein; Liver X Receptor; Liver X Receptor Alpha; Liver X Receptor Beta; Liver X Receptor-Alpha; Liver X Receptor-Beta; NR1H2 Protein; NR1H3 Protein; Nuclear Orphan Receptor LXR-Alpha; Nuclear Oxysterol Receptors; Nuclear Receptor Subfamily 1, Group H, Member 2; Nuclear Receptor Subfamily 1, Group H, Member 3; Oxysterols Receptor LXR-Alpha; Oxysterols Receptor LXR-Beta
Public MeSH Note: 2017; LIVER X RECEPTORS was indexed under ORPHAN NUCLEAR RECEPTORS 2009-2016; and under DNA-BINDING PROTEINS and RECEPTORS, CYTOPLASMIC AND NUCLEAR 2002-2009
History Note: 2017 (2002)
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/04/20

Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Concept UI: M0246645
Scope Note: A liver X receptor that is expressed primarily by cells in the liver and other metabolically-active tissues.
Terms: Liver X Receptor Alpha Preferred Term
Term UI T000895794
Date02/23/2016
LexicalTag NON
ThesaurusID NLM (2002); Liver X Receptor-Alpha
Term UI T000895795
Date02/23/2016
LexicalTag NON
ThesaurusID NLM (2017); LXR-Alpha Protein
Term UI T000895796
Date02/23/2016
LexicalTag NON
ThesaurusID NLM (2002); LXRalpha Protein
Term UI T000895797
Date02/23/2016
LexicalTag NON
ThesaurusID NLM (2002); Nuclear Orphan Receptor LXR-Alpha
Term UI T000895798
Date02/23/2016
LexicalTag NON
ThesaurusID NLM (2005); Oxysterols Receptor LXR-Alpha
Term UI T000895799
Date02/23/2016
LexicalTag NON
ThesaurusID NLM (2002); Nuclear Receptor Subfamily 1, Group H, Member 3
Term UI T000895793
Date02/23/2016
LexicalTag NON
ThesaurusID NLM (2009); NR1H3 Protein
Term UI T000899004
Date04/15/2016
LexicalTag NON
ThesaurusID NLM (2017)

Concept UI: M000614998
Scope Note: A liver X receptor that is ubiquitously expressed. Loss of LXR-beta function is associated with an increase in the expression of UNCOUPLING PROTEIN 1 as well as OBESITY.
Terms: Liver X Receptor Beta Preferred Term
Term UI T000895787
Date02/23/2016
LexicalTag NON
ThesaurusID NLM (2002); Liver X Receptor-Beta
Term UI T000895800
Date02/23/2016
LexicalTag NON
ThesaurusID NLM (2017); LXRbeta Protein
Term UI T000895789
Date02/23/2016
LexicalTag ABX
ThesaurusID NLM (2002); NR1H2 Protein
Term UI T000895790
Date02/23/2016
LexicalTag ABX
ThesaurusID NLM (2001); Nuclear Receptor Subfamily 1, Group H, Member 2
Term UI T000895791
Date02/23/2016
LexicalTag NON
ThesaurusID NLM (2009); Oxysterols Receptor LXR-Beta
Term UI T000895792
Date02/23/2016
LexicalTag ABX
ThesaurusID NLM (2002)

Liver X Receptors MeSH Descriptor Data 2025