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Interferon-Stimulated Gene Factor 3 MeSH Descriptor Data 2026


MeSH Heading
Interferon-Stimulated Gene Factor 3
Tree Number(s)
D12.644.360.024.303
D12.776.157.057.061
D12.776.260.513
D12.776.476.024.386
D12.776.930.354
Unique ID
D050832
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D050832
Scope Note
A multimeric complex that functions as a ligand-dependent transcription factor. ISGF3 is assembled in the CYTOPLASM and translocated to the CELL NUCLEUS in response to INTERFERON signaling. It consists of ISGF3-GAMMA and ISGF3-ALPHA, and it regulates expression of many interferon-responsive GENES.
Entry Term(s)
IFN-Stimulated Gene Factor 3 Complex
ISGF3 Factor
ISGF3 Transcription Factor
Transcription Factor ISGF3
Registry Numbers
0
Public MeSH Note
2006; INTERFERON-STIMULATED GENE FACTOR 3 was indexed under DNA-BINDING PROTEINS & TRANSCRIPTION FACTORS 1990-2005
History Note
2006(1990)
Date Introduced
2006/01/01
Last Updated
2015/11/23
Interferon-Stimulated Gene Factor 3 Preferred
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