MeSH Browser

MeSH Heading: Protein Inhibitors of Activated STAT
Tree Number(s): D12.644.360.024.319; D12.776.157.057.124; D12.776.476.024.402
Unique ID: D050828
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D050828
Scope Note: A family of structurally related proteins that are constitutively expressed and that negatively regulate cytokine-mediated SIGNAL TRANSDUCTION PATHWAYS. PIAS proteins inhibit the activity of signal transducers and activators of transcription.
Entry Term(s): PIAS Proteins; PIAS1 Protein; PIAS1 Protein Inhibitor of Activated STAT; PIAS2 Protein Inhibitor of Activated STAT; PIAS3 Protein Inhibitor of Activated STAT; PIAS4 Protein Inhibitor of Activated STAT
Public MeSH Note: 2006; PROTEIN INHIBITORS OF ACTIVATED STAT was indexed under PROTEINS 1998-2005
History Note: 2006(1998)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/03/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Protein Inhibitors of Activated STAT MeSH Descriptor Data 2025