MeSH Browser

MeSH Heading: Cortactin
Tree Number(s): D05.750.078.730.281; D12.644.360.024.280; D12.776.157.057.014; D12.776.220.525.281; D12.776.476.024.311; D12.776.744.390
Unique ID: D051356
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051356
Scope Note: A microfilament protein that interacts with F-ACTIN and regulates cortical actin assembly and organization. It is also an SH3 DOMAIN containing phosphoprotein, and it mediates tyrosine PHOSPHORYLATION based SIGNAL TRANSDUCTION by PROTO-ONCOGENE PROTEIN PP60(C-SRC).
Public MeSH Note: 2006; CORTACTIN was indexed under MICROFILAMENT PROTEINS 1993-2005
History Note: 2006(1983)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2015/11/23

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Cortactin MeSH Descriptor Data 2025