MeSH Browser

MeSH Heading: Plectin
Tree Number(s): D12.776.220.790.750; D12.776.744.736
Unique ID: D051190
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051190
Scope Note: A cytoskeletal linker protein with a molecular weight of greater than 500 kDa. It binds INTERMEDIATE FILAMENTS; MICROTUBULES; and ACTIN CYTOSKELETON and plays a central role in the organization and stability of the CYTOSKELETON. Plectin is phosphorylated by CALMODULIN KINASE; PROTEIN KINASE A; and PROTEIN KINASE C.
Entry Term(s): 500-kDa HD1 Protein; Hemidesmosomal Protein HD1
Public MeSH Note: 2006; PLECTIN was indexed under INTERMEDIATE FILAMENT PROTEINS 1992-2005, & under PROTEINS 1982-1991
History Note: 2006(1982)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2011/07/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Plectin MeSH Descriptor Data 2025