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Protein Kinase C MeSH Descriptor Data 2022


MeSH Heading
Protein Kinase C
Tree Number(s)
D08.811.913.696.620.682.700.725
D12.776.476.563.725
Unique ID
D011493
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D011493
Scope Note
An serine-threonine protein kinase that requires the presence of physiological concentrations of CALCIUM and membrane PHOSPHOLIPIDS. The additional presence of DIACYLGLYCEROLS markedly increases its sensitivity to both calcium and phospholipids. The sensitivity of the enzyme can also be increased by PHORBOL ESTERS and it is believed that protein kinase C is the receptor protein of tumor-promoting phorbol esters.
Entry Term(s)
Calcium Phospholipid-Dependent Protein Kinase
Calcium-Activated Phospholipid-Dependent Kinase
PKC Serine-Threonine Kinase
Phospholipid-Sensitive Calcium-Dependent Protein Kinase
Protein Kinase M
Registry Number
EC 2.7.11.13
Previous Indexing
Protein Kinases (1973-1985)
Public MeSH Note
86; CALCIUM PHOSPHOLIPID-DEPENDENT PROTEIN KINASE was CALCIUM-PHOSPHOLIPID DEPENDENT PROTEIN KINASE 1986-93
History Note
86; CALCIUM PHOSPHOLIPID-DEPENDENT PROTEIN KINASE was CALCIUM-PHOSPHOLIPID DEPENDENT PROTEIN KINASE 1986-93
Date Established
1986/01/01
Date of Entry
1985/05/17
Revision Date
2021/05/21
Protein Kinase C Preferred
Protein Kinase M Narrower
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