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Ataxia Telangiectasia Mutated Proteins MeSH Descriptor Data 2026
A group of PROTEIN SERINE-THREONINE KINASES which activate critical signaling cascades in double strand breaks, APOPTOSIS, and GENOTOXIC STRESS such as ionizing ultraviolet A light, thereby acting as a DNA damage sensor. These proteins play a role in a wide range of signaling mechanisms in cell cycle control.
Entry Term(s)
A-T Protein
AT Mutated Protein
ATM Protein
Registry Numbers
EC 2.7.11.1
Public MeSH Note
2014; was indexed under PROTEIN KINASES 1983-1992; PROTEIN-SERINE-THREONINE KINASES 1993-2013
A group of PROTEIN SERINE-THREONINE KINASES which activate critical signaling cascades in double strand breaks, APOPTOSIS, and GENOTOXIC STRESS such as ionizing ultraviolet A light, thereby acting as a DNA damage sensor. These proteins play a role in a wide range of signaling mechanisms in cell cycle control.