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Receptor, Transforming Growth Factor-beta Type II MeSH Descriptor Data 2022


MeSH Heading
Receptor, Transforming Growth Factor-beta Type II
Tree Number(s)
D08.811.913.696.620.682.700.795
D12.776.476.563.795
D12.776.543.750.705.852.720.750
D12.776.543.750.750.400.820.875
Unique ID
D000077294
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077294
Scope Note
A transmembrane serine-threonine kinase that forms a heteromeric complex with TYPE I TGF-BETA RECEPTORS when bound to TGF-BETA. This receptor complex regulates a variety of physiological and pathological processes including CELL CYCLE ARREST; CELL PROLIFERATION; CELL DIFFERENTIATION; WOUND HEALING; EXTRACELLULAR MATRIX production, immunosuppression and ONCOGENESIS.
Entry Term(s)
TGF-beta Type II Receptor
TGF-beta Type II Receptors
TGFBR2
TbetaR-II Kinase
Transforming Growth Factor-beta Type II Receptor
Transforming Growth Factor-beta Type II Receptors
Type II TGF-beta Receptor
Type II TGF-beta Receptors
Registry Number
EC 2.7.11.30
Public MeSH Note
2019; see TRANSFORMING GROWTH FACTOR-BETA TYPE II RECEPTOR 1993-2018; RECEPTOR, TRANSFORMING GROWTH FACTOR-BETA TYPE II was indexed under PROTEIN-SERINE-THREONINE KINASES and RECEPTORS, TRANSFORMING GROWTH FACTOR BETA 1994-2018; and under RECEPTORS, ENDOGENOUS SUBSTANCES 1993
History Note
2019 (1993)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2021/05/21
Receptor, Transforming Growth Factor-beta Type II Preferred
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