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Serine protein kinases involved in the regulation of ACTIN polymerization and MICROTUBULE disassembly. Their activity is regulated by phosphorylation of a threonine residue within the activation loop by intracellular signaling kinases such as P21-ACTIVATED KINASES and by RHO KINASE.
Entry Term(s)
LIM Kinase
LIM Motif-Containing Protein Kinases
LIM-Kinase
Registry Numbers
EC 2.7.11.1
Public MeSH Note
2008; LIM KINASES was indexed under PROTEIN KINASES 1995-2007
Serine protein kinases involved in the regulation of ACTIN polymerization and MICROTUBULE disassembly. Their activity is regulated by phosphorylation of a threonine residue within the activation loop by intracellular signaling kinases such as P21-ACTIVATED KINASES and by RHO KINASE.