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p21-Activated Kinases MeSH Descriptor Data 2023


MeSH Heading
p21-Activated Kinases
Tree Number(s)
D08.811.913.696.620.682.700.596
D12.776.476.563.596
Unique ID
D054462
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D054462
Scope Note
A family of serine-threonine kinases that bind to and are activated by MONOMERIC GTP-BINDING PROTEINS such as RAC GTP-BINDING PROTEINS and CDC42 GTP-BINDING PROTEIN. They are intracellular signaling kinases that play a role the regulation of cytoskeletal organization.
Entry Term(s)
Oligophrenin-3
PAK Kinase
PAK Kinases
PAK-1 Kinase
PAK-2 Kinase
PAK1 Kinase
PAK2 Kinase
PAK3 Kinase
PAK65
Serine-Threonine-Protein Kinase PAK 1
Serine-Threonine-Protein Kinase PAK 3
alpha p21-Activated Kinase
alpha-PAK
beta p21-Activated Kinase
beta-PAK
gamma-PAK
p21-Activated Kinase
p21-Activated Kinase 1
p21-Activated Kinase 2
p21-Activated Kinase 3
p65(PAK)
p65PAK Protein
Registry Number
EC 2.7.11.1
Related Numbers
EC 2.7.11.1
Previous Indexing
Protein-Serine-Threonine Kinases (1995-2007)
Public MeSH Note
2008; P21-ACTIVATED KINASE 1, P21-ACTIVATED KINASE 2 & P21-ACTIVATED KINASE 3 were indexed under PROTEIN-SERINE-THREONINE KINASES 1995-2007
History Note
2008
Date Established
2008/01/01
Date of Entry
2007/07/09
Revision Date
2021/06/28
p21-Activated Kinases Preferred
p21-Activated Kinase 2 Narrower
p21-Activated Kinase 1 Narrower
p21-Activated Kinase 3 Narrower
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