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MAP Kinase Kinase Kinases MeSH Descriptor Data 2023


MeSH Heading
MAP Kinase Kinase Kinases
Tree Number(s)
D08.811.913.696.620.682.700.559
D12.776.476.563.554
Unique ID
D020930
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D020930
Scope Note
Mitogen-activated protein kinase kinase kinases (MAPKKKs) are serine-threonine protein kinases that initiate protein kinase signaling cascades. They phosphorylate MITOGEN-ACTIVATED PROTEIN KINASE KINASES; (MAPKKs) which in turn phosphorylate MITOGEN-ACTIVATED PROTEIN KINASES; (MAPKs).
Entry Term(s)
Kinases, MAP Kinase Kinase
MAP Kinase Kinase Kinase
MAP3 Kinase
MAP3 Kinases
MAPK-ERK Kinase Kinase
MAPK-ERK Kinase Kinases
MAPKKK
MAPKKKs
MEK Kinase
MEK Kinases
MEKK
MEKKs
Mitogen-Activated Protein Kinase Kinase Kinase
Mitogen-Activated Protein Kinase Kinase Kinases
Registry Number
EC 2.7.11.25
Related Numbers
EC 2.7.11.25
Previous Indexing
Protein Kinases (1989-1999)
Protein-Serine-Threonine Kinases (1993-1999)
Protein-Tyrosine Kinase (1989-1999)
See Also
MAP Kinase Signaling System
Public MeSH Note
2000; MAP KINASE KINASE KINASE (now MAP KINASE KINASE KINASES) was indexed under PROTEIN-SERINE-THREONINE KINASES 1992-1999
History Note
2000; use MAP KINASE KINASE KINASE 1992-1999
Date Established
2000/01/01
Date of Entry
1999/11/03
Revision Date
2021/04/22
MAP Kinase Kinase Kinases Preferred
MAPK-ERK Kinase Kinases Narrower
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