Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

NLM Logo

raf Kinases MeSH Descriptor Data 2026


MeSH Heading
raf Kinases
Tree Number(s)
D08.811.913.696.620.682.700.559.842
D12.776.476.563.554.842
D12.776.624.664.700.204
Unique ID
D048490
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D048490
Scope Note
A family of closely-related serine-threonine kinases that were originally identified as the cellular homologs of the retrovirus-derived V-RAF KINASES. They are MAP kinase kinase kinases that play important roles in SIGNAL TRANSDUCTION.
Entry Term(s)
MIL-RAF Proteins
Proto-Oncogene Proteins raf
mil-raf Protein Kinases
raf Kinase
raf MAP Kinase Kinase Kinases
raf Proto-Oncogene Proteins
raf Serine-Theonine Protein Kinases
Registry Numbers
EC 2.7.11.1
EC 2.7.11.1
Related Numbers
EC 2.7.11.1
Previous Indexing
Proto-Oncogene Proteins c-raf (1986-2004)
Public MeSH Note
2005; MIL-RAF PROTEIN KINASES & MIL-RAF PROTEINS was indexed under PROTEIN-SERINE-THREONINE KINASES 1993-97 & PROTO-ONCOGENE PROTEINS 1986-97
History Note
2005
Date Introduced
2005/01/01
Last Updated
2021/05/21
raf Kinases Preferred
mil-raf Protein Kinases Narrower
page delivered in 0.2s