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Proto-Oncogene Proteins p21(ras) MeSH Descriptor Data 2023


MeSH Heading
Proto-Oncogene Proteins p21(ras)
Tree Number(s)
D08.811.277.040.330.300.400.500.600
D12.776.157.325.515.500.600
D12.776.476.338.400.500.600
D12.776.624.664.700.200
Unique ID
D016283
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016283
Scope Note
Cellular proteins encoded by the H-ras, K-ras and N-ras genes. The proteins have GTPase activity and are involved in signal transduction as monomeric GTP-binding proteins. Elevated levels of p21 c-ras have been associated with neoplasia. This enzyme was formerly listed as EC 3.6.1.47.
Entry Term(s)
Proto-Oncogene Protein p21(c-Ha-ras)
Proto-Oncogene Protein p21(c-Ki-ras)
Proto-Oncogene Protein p21(c-N-ras)
Proto-Oncogene Protein p21(ras)
Proto-Oncogene Protein ras
Proto-Oncogene Proteins c-ras
c-Ha-ras p21
c-Ki-ras p21
c-ras Proteins
p21 c-H-ras
p21 c-Ha-ras
p21 c-K-ras
p21 c-Ki-ras
p21 c-ras
p21(N-ras)
p21(c-Ha-ras)
p21(c-Ki-ras)
p21(c-ras)
p21(ras)
ras Proto-Oncogene Product p21
ras Proto-Oncogene Protein p21
Registry Number
EC 3.6.5.2
Previous Indexing
Neoplasm Proteins (1983-1986)
Proto-Oncogene Proteins (1987-1990)
See Also
Costello Syndrome
Public MeSH Note
2006; for P21(RAS) see ONCOGENE PROTEIN P21(RAS) 1990
History Note
2006(1991)
Date Established
1991/01/01
Date of Entry
1990/06/19
Revision Date
2021/05/21
Proto-Oncogene Proteins p21(ras) Preferred
Proto-Oncogene Protein p21(c-N-ras) Narrower
Proto-Oncogene Protein p21(c-Ha-ras) Narrower
Proto-Oncogene Protein p21(c-Ki-ras) Narrower
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