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Proto-Oncogene Proteins c-rel MeSH Descriptor Data 2023


MeSH Heading
Proto-Oncogene Proteins c-rel
Tree Number(s)
D12.776.260.682
D12.776.624.664.700.192
D12.776.660.767
D12.776.930.730
Unique ID
D020569
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D020569
Scope Note
Cellular DNA-binding proteins encoded by the rel gene (GENES, REL). They are expressed predominately in hematopoietic cells and may play a role in lymphocyte differentiation. Rel frequently combines with other related proteins (NF-KAPPA B, I-kappa B, relA) to form heterodimers that regulate transcription. Rearrangement or overexpression of c-rel can cause tumorigenesis.
Entry Term(s)
Proto-Oncogene Products c-rel
Proto-Oncogene Protein c-rel
Proto-Oncogene Proteins rel
c-rel Protein
c-rel Proteins
p68 c-rel
p68(c-rel)
rel Proto-Oncogene Product p68
rel Proto-Oncogene Proteins
Registry Number
0
Previous Indexing
Proto-Oncogene Proteins (1988-1999)
See Also
Genes, rel
I-kappa B Proteins
Public MeSH Note
2000; PROTO-ONCOGENE PROTEIN C-REL was indexed under PROTO-ONCOGENE PROTEINS 1988-1999
History Note
2000; use PROTO-ONCOGENE PROTEINS C-REL (NM) 1988-1999
Date Established
2000/01/01
Date of Entry
1999/11/08
Revision Date
2015/06/29
Proto-Oncogene Proteins c-rel Preferred
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