MeSH Browser

MeSH Heading: SOX Transcription Factors
Tree Number(s): D12.776.260.719; D12.776.660.235.400.750; D12.776.664.235.400.750; D12.776.930.823
Unique ID: D055747
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D055747
Annotation: do not confuse entry term SRY (SEX DETERMINING REGION Y)-BOX PROTEINS with SRY SEX-DETERMINING REGION PROTEIN see SEX-DETERMINING REGION Y PROTEIN
Scope Note: A large family of structurally-related transcription factors that were originally discovered based upon their close sequence homology to an HMG-box domain found in SEX-DETERMINING REGION Y PROTEIN. Many SOX transcription factors play important roles in regulating CELL DIFFERENTIATION. The numerous members of this family are organized in several subgroups according to structural identities found within the proteins.
Entry Term(s): SOX Family of Transcription Factors; SOX Transcription Factor Family; SRY (Sex Determining Region Y)-Box Proteins
Previous Indexing: DNA-Binding Proteins (1992-2008); HMG Proteins (1992-2008); Transcription Factors (1992-2008)
Public MeSH Note: 2009
History Note: 2009
Date Established: 2009/01/01
Date of Entry: 2008/07/08
Revision Date: 2009/07/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0519997
Scope Note: A large family of structurally-related transcription factors that were originally discovered based upon their close sequence homology to an HMG-box domain found in SEX-DETERMINING REGION Y PROTEIN. Many SOX transcription factors play important roles in regulating CELL DIFFERENTIATION. The numerous members of this family are organized in several subgroups according to structural identities found within the proteins.
Terms: SOX Transcription Factors Preferred Term
Term UI T717347
Date04/03/2008
LexicalTag ABX
ThesaurusID NLM (2009); SOX Family of Transcription Factors
Term UI T717369
Date04/03/2008
LexicalTag ABX
ThesaurusID NLM (2009); SOX Transcription Factor Family
Term UI T717370
Date04/03/2008
LexicalTag ABX
ThesaurusID NLM (2009); SRY (Sex Determining Region Y)-Box Proteins
Term UI T717348
Date04/03/2008
LexicalTag ABX
ThesaurusID NLM (2009)

SOX Transcription Factors MeSH Descriptor Data 2025