MeSH Browser

MeSH Heading: Host Cell Factor C1
Tree Number(s): D12.776.660.478; D12.776.930.325
Unique ID: D051863
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051863
Scope Note: A cellular transcriptional coactivator that contains N-terminal KELCH REPEATS and N- and C-terminal FIBRONECTIN TYPE III DOMAINS. It functions as a transcription factor for a number of genes and in the assembly of IMMEDIATE-EARLY PROTEINS of the HERPES SIMPLEX VIRUS. Mutations in the HCFC1 gene are associated with cases of X-LINKED MENTAL RETARDATION.
Entry Term(s): C1 Host Cell Factor; Cell Proliferation Factor HCF; HCFC1 Protein
Public MeSH Note: 2006; HOST CELL FACTOR C1 was indexed under TRANSCRIPTION FACTORS 1995-2005
History Note: 2006(1995)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0241725
Scope Note: A cellular transcriptional coactivator that contains N-terminal KELCH REPEATS and N- and C-terminal FIBRONECTIN TYPE III DOMAINS. It functions as a transcription factor for a number of genes and in the assembly of IMMEDIATE-EARLY PROTEINS of the HERPES SIMPLEX VIRUS. Mutations in the HCFC1 gene are associated with cases of X-LINKED MENTAL RETARDATION.
Terms: Host Cell Factor C1 Preferred Term
Term UI T271730
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); HCFC1 Protein
Term UI T000897922
Date03/30/2016
LexicalTag ABX
ThesaurusID NLM (2017); C1 Host Cell Factor
Term UI T271724
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2006); Cell Proliferation Factor HCF
Term UI T271729
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2006)

Host Cell Factor C1 MeSH Descriptor Data 2025