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Elongin MeSH Descriptor Data 2023


MeSH Heading
Elongin
Tree Number(s)
D12.776.260.197
D12.776.930.215
Unique ID
D000075065
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000075065
Scope Note
A heterotrimeric protein complex composed of 110 kDa elongin A, 18 kDa elongin B, and 15 kDa elongin C subunits. It functions as a positive regulator of RNA POLYMERASE II, increasing its rate of transcriptional elongation by suppressing transient pausing along the DNA template. Elongin A is the transcriptionally active component; elongins B and C enhance its activity.
Entry Term(s)
EloA Protein
EloB Protein
EloC Protein
Elongin A
Elongin B
Elongin C
Elongin Complex
SIII Elongation Factor
TF-SIII
Transcription Factor SIII
Registry Number
0
Public MeSH Note
2018; ELONGIN was indexed under TRANSCRIPTION FACTORS 1995-2017
History Note
2018 (1995)
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2017/05/22
Elongin Preferred
Elongin C Narrower
Elongin A Narrower
Elongin B Narrower
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