MeSH Browser

MeSH Heading: Methyl-CpG-Binding Protein 2
Tree Number(s): D12.776.260.536; D12.776.660.235.550; D12.776.664.235.700
Unique ID: D051783
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051783
Scope Note: A DNA-binding protein that interacts with methylated CPG ISLANDS. It plays a role in repressing GENETIC TRANSCRIPTION and is frequently mutated in RETT SYNDROME.
Entry Term(s): MeCP2 Protein
See Also: Methyl CpG Binding Domain; Rett Syndrome
Public MeSH Note: 2006; METHYL-CPG-BINDING PROTEIN 2 was indexed under CHROMOSOMAL PROTEINS, NON-HISTONE & DNA-BINDING PROTEINS & REPRESSOR PROTEINS 2005, & under TRANSCRIPTION FACTORS 1992-2004
History Note: 2006(1992)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2015/11/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Methyl-CpG-Binding Protein 2 MeSH Descriptor Data 2025