MeSH Browser

MeSH Heading: POU Domain Factors
Tree Number(s): D12.776.260.655; D12.776.930.710
Unique ID: D050809
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D050809
Scope Note: A family of transcription factors characterized by the presence of a bipartite DNA-binding domain known as the POU domain. The POU domain contains two subdomains, a POU-specific domain and a POU-homeodomain. The POU domain was originally identified as a region of approximately 150 amino acids shared between the Pit-1, Oct-1, Oct-2, and Unc-86 transcription factors.
Entry Term(s): POU Proteins; Pit-Oct-Unc Proteins; Transcription Factor POU
Public MeSH Note: 2006; TRANSCRIPTION FACTOR POU was indexed under DNA-BINDING PROTEINS & TRANSCRIPTION FACTORS 1992-2004
History Note: 2006(1992)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2015/06/29

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0208075
Scope Note: A family of transcription factors characterized by the presence of a bipartite DNA-binding domain known as the POU domain. The POU domain contains two subdomains, a POU-specific domain and a POU-homeodomain. The POU domain was originally identified as a region of approximately 150 amino acids shared between the Pit-1, Oct-1, Oct-2, and Unc-86 transcription factors.
Terms: POU Domain Factors Preferred Term
Term UI T624747
Date12/20/2004
LexicalTag ACX
ThesaurusID NLM (2006); Transcription Factor POU
Term UI T238080
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2006); POU Proteins
Term UI T624748
Date12/20/2004
LexicalTag ACX
ThesaurusID NLM (2006); Pit-Oct-Unc Proteins
Term UI T624749
Date12/20/2004
LexicalTag ABX
ThesaurusID NLM (2006)

POU Domain Factors MeSH Descriptor Data 2025