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Tumor Suppressor p53-Binding Protein 1 MeSH Descriptor Data 2023


MeSH Heading
Tumor Suppressor p53-Binding Protein 1
Tree Number(s)
D12.776.260.805
D12.776.660.235.850
D12.776.664.235.950
Unique ID
D000071857
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071857
Scope Note
A nuclear and cytoplasmic protein that associates with KINETOCHORES and contains a C-terminal TUDOR DOMAIN. It plays a critical role in the cellular response to DNA DAMAGE and localizes to DOUBLE-STRAND DNA BREAKS. It may also function in M PHASE CELL CYCLE CHECKPOINTS and as an enhancer of TUMOR SUPPRESSOR PROTEIN P53-mediated transcriptional activation.
Entry Term(s)
53BP1 Protein
TP53BP1 Protein
Tumor Protein p53-Binding Protein, 1
p202 Protein
Registry Number
0
Previous Indexing
Chromosomal Proteins, Non-Histone (2005-2016)
DNA-Binding Proteins (2005-2016)
Intracellular Signaling Peptides and Proteins (2005-2016)
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/07/05
Tumor Suppressor p53-Binding Protein 1 Preferred
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