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Retinoblastoma Protein MeSH Descriptor Data 2023


MeSH Heading
Retinoblastoma Protein
Tree Number(s)
D12.776.260.704
D12.776.624.776.745
D12.776.660.807
D12.776.744.770
Unique ID
D016160
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016160
Annotation
/biosyn /‌drug eff /‌physiol /‌ultrastruct permitted
Scope Note
Product of the retinoblastoma tumor suppressor gene. It is a nuclear phosphoprotein hypothesized to normally act as an inhibitor of cell proliferation. Rb protein is absent in retinoblastoma cell lines. It also has been shown to form complexes with the adenovirus E1A protein, the SV40 T antigen, and the human papilloma virus E7 protein.
Entry Term(s)
Rb Gene Product
Rb Protein
Rb1 Gene Product
Retinoblastoma Nuclear Phosphoprotein p105-Rb
p105-Rb Protein
Registry Number
0
Previous Indexing
Phosphoproteins (1990)
Public MeSH Note
91
History Note
91
Date Established
1991/01/01
Date of Entry
1990/06/19
Revision Date
2005/06/30
Retinoblastoma Protein Preferred
p105-Rb Protein Narrower
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