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Von Hippel-Lindau Tumor Suppressor Protein MeSH Descriptor Data 2023


MeSH Heading
Von Hippel-Lindau Tumor Suppressor Protein
Tree Number(s)
D08.811.464.938.750.875
D12.776.624.776.865
Unique ID
D051794
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D051794
Scope Note
A ubiquitin-protein ligase that mediates OXYGEN-dependent polyubiquitination of HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT. It is inactivated in VON HIPPEL-LINDAU SYNDROME.
Entry Term(s)
VHL Tumor Suppressor Protein
Registry Number
EC 2.3.2.27
Public MeSH Note
2006; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN was indexed under TUMOR SUPPRESSOR PROTEINS 2002-2005, under UBIQUITIN-PROTEIN LIGASES 2004-2005, under LIGASES 2002-3003, under PROTEINS 1995-2001, & under NUCLEAR PROTEINS 1995
History Note
2006 (1995)
Entry Combination
deficiency:von Hippel-Lindau Disease
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2016/06/02
Von Hippel-Lindau Tumor Suppressor Protein Preferred
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