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BRCA1 Protein MeSH Descriptor Data 2026


MeSH Heading
BRCA1 Protein
Tree Number(s)
D12.776.313.125
D12.776.624.776.100
D12.776.660.100
D12.776.744.100
D12.776.930.137
Unique ID
D019313
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019313
Scope Note
The phosphoprotein encoded by the BRCA1 gene (GENE, BRCA1). It contains an N-terminal RING FINGER DOMAIN and is a PROTEIN PHOSPHATASE 1 regulatory subunit. In normal cells the BRCA1 protein is localized in the nucleus, whereas in the majority of breast cancer cell lines and in malignant pleural effusions from breast cancer patients, it is localized mainly in the cytoplasm. (Science 1995;270(5237):713,789-91)
Entry Term(s)
BRCA1 Gene Product
Breast Cancer 1 Gene Product
Breast Cancer 1 Protein
Breast Cancer Type 1 Susceptibility Protein
Ring Finger Protein 53
Registry Numbers
0
NLM Classification #
WP 870
Previous Indexing
Neoplasm Proteins (1994-1996)
Transcription Factors (1994-1996)
See Also
Genes, BRCA1
Hereditary Breast and Ovarian Cancer Syndrome
Public MeSH Note
97; BCRA1 PROTEIN was indexed under NEOPLASM PROTEINS & TRANSCRIPTION FACTORS 1994-96
Online Note
use BRCA1 PROTEIN (NM) to search BRCA1 PROTEIN 1994-96
History Note
97; was BRCA1 PROTEIN (NM) 1994-96
Date Introduced
1997/01/01
Last Updated
2015/11/23
BRCA1 Protein Preferred
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