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RING Finger Domains MeSH Descriptor Data 2022


MeSH Heading
RING Finger Domains
Tree Number(s)
G02.111.570.820.709.275.500.985.500
G02.111.570.820.709.275.750.500.625
Unique ID
D054829
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D054829
Scope Note
A zinc-binding domain defined by the sequence Cysteine-X2-Cysteine-X(9-39)-Cysteine-X(l-3)-His-X(2-3)-Cysteine-X2-Cysteine -X(4-48)-Cysteine-X2-Cysteine, where X is any amino acid. The RING finger motif binds two atoms of zinc, with each zinc atom ligated tetrahedrally by either four cysteines or three cysteines and a histidine. The motif also forms into a unitary structure with a central cross-brace region and is found in many proteins that are involved in protein-protein interactions. The acronym RING stands for Really Interesting New Gene.
Entry Term(s)
RING Finger Motifs
Public MeSH Note
2008
History Note
2008
Date Established
2008/01/01
Date of Entry
2007/07/09
Revision Date
2016/05/31
RING Finger Domains Preferred
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