MeSH Browser

MeSH Heading: WD40 Repeats
Tree Number(s): G02.111.570.060.720.515; G02.111.570.820.709.275.500.927; G02.111.570.820.709.275.750.500.875; G02.111.570.820.709.275.875.515
Unique ID: D000071678
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000071678
Scope Note: Protein interaction motifs of approximately 40 amino acids that usually terminate in TRYPTOPHAN and ASPARTIC ACID. They form characteristic beta-propeller structures and occur in many eukaryotic proteins that function in a variety of cellular processes. Proteins that contain WD40 repeats often function as assembly platforms for MULTIPROTEIN COMPLEXES.
Entry Term(s): WD Repeats; WD40 Motif; WD40 Repeat; beta-Transducin Repeats
Previous Indexing: Amino Acid Sequence (1994-2016); Repetitive Sequences, Amino Acid (1999-2016)
Public MeSH Note: 2017
History Note: 2017
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/05/09

Allowable Qualifiers: drug effects (DE)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Chemical Phenomena [G02]
- Biochemical Phenomena [G02.111]
  - Molecular Structure [G02.111.570]
    - Amino Acid Sequence [G02.111.570.060]
      - Repetitive Sequences, Amino Acid [G02.111.570.060.720]
        
        Ankyrin Repeat [G02.111.570.060.720.030]
        
        Kelch Repeat [G02.111.570.060.720.273]
        
        Tetratricopeptide Repeat [G02.111.570.060.720.394]
        
        WD40 Repeats [G02.111.570.060.720.515]

Chemical Phenomena [G02]
- Biochemical Phenomena [G02.111]
  - Molecular Structure [G02.111.570]
    - Molecular Conformation [G02.111.570.820]
      - Protein Conformation [G02.111.570.820.709]
        
        Protein Structural Elements [G02.111.570.820.709.275]
        
        Amino Acid Motifs [G02.111.570.820.709.275.500]
        
        Ankyrin Repeat [G02.111.570.820.709.275.500.030]
        
        AT-Hook Motifs [G02.111.570.820.709.275.500.050]
        
        Cystine Knot Motifs [G02.111.570.820.709.275.500.127]
        
        F-Box Motifs [G02.111.570.820.709.275.500.205]
        
        Helix-Loop-Helix Motifs [G02.111.570.820.709.275.500.360]
        
        Immunoreceptor Tyrosine-Based Activation Motif [G02.111.570.820.709.275.500.440]
        
        Immunoreceptor Tyrosine-Based Inhibition Motif [G02.111.570.820.709.275.500.480]
        
        Kazal Motifs [G02.111.570.820.709.275.500.490]
        
        Kelch Repeat [G02.111.570.820.709.275.500.500]
        
        Leucine Zippers [G02.111.570.820.709.275.500.520]
        
        Poly-ADP-Ribose Binding Motif [G02.111.570.820.709.275.500.695]
        
        RNA-Binding Motifs [G02.111.570.820.709.275.500.869]
        
        Sterile Alpha Motif [G02.111.570.820.709.275.500.898]
        
        AAA Domain [G02.111.570.820.709.275.500.913]
        
        Tetratricopeptide Repeat [G02.111.570.820.709.275.500.920]
        
        WD40 Repeats [G02.111.570.820.709.275.500.927]
        
        Zinc Fingers [G02.111.570.820.709.275.500.985]

Chemical Phenomena [G02]
- Biochemical Phenomena [G02.111]
  - Molecular Structure [G02.111.570]
    - Molecular Conformation [G02.111.570.820]
      - Protein Conformation [G02.111.570.820.709]
        
        Protein Structural Elements [G02.111.570.820.709.275]
        
        Protein Domains [G02.111.570.820.709.275.750]
        
        Protein Interaction Domains and Motifs [G02.111.570.820.709.275.750.500]
        
        Ankyrin Repeat [G02.111.570.820.709.275.750.500.080]
        
        B30.2-SPRY Domain [G02.111.570.820.709.275.750.500.290]
        
        BTB-POZ Domain [G02.111.570.820.709.275.750.500.343]
        
        Death Domain Superfamily [G02.111.570.820.709.275.750.500.395]
        
        FERM Domains [G02.111.570.820.709.275.750.500.422]
        
        Kelch Repeat [G02.111.570.820.709.275.750.500.448]
        
        MYND Domains [G02.111.570.820.709.275.750.500.474]
        
        PDZ Domains [G02.111.570.820.709.275.750.500.500]
        
        RING Finger Domains [G02.111.570.820.709.275.750.500.625]
        
        src Homology Domains [G02.111.570.820.709.275.750.500.750]
        
        Sterile Alpha Motif [G02.111.570.820.709.275.750.500.813]
        
        Tetratricopeptide Repeat [G02.111.570.820.709.275.750.500.829]
        
        Tudor Domain [G02.111.570.820.709.275.750.500.844]
        
        WD40 Repeats [G02.111.570.820.709.275.750.500.875]
        
        WW Domains [G02.111.570.820.709.275.750.500.937]

Chemical Phenomena [G02]
- Biochemical Phenomena [G02.111]
  - Molecular Structure [G02.111.570]
    - Molecular Conformation [G02.111.570.820]
      - Protein Conformation [G02.111.570.820.709]
        
        Protein Structural Elements [G02.111.570.820.709.275]
        
        Repetitive Sequences, Amino Acid [G02.111.570.820.709.275.875]
        
        Ankyrin Repeat [G02.111.570.820.709.275.875.030]
        
        Kelch Repeat [G02.111.570.820.709.275.875.273]
        
        Tetratricopeptide Repeat [G02.111.570.820.709.275.875.394]
        
        WD40 Repeats [G02.111.570.820.709.275.875.515]

WD40 Repeats Preferred

Concept UI: M000615307
Scope Note: Protein interaction motifs of approximately 40 amino acids that usually terminate in TRYPTOPHAN and ASPARTIC ACID. They form characteristic beta-propeller structures and occur in many eukaryotic proteins that function in a variety of cellular processes. Proteins that contain WD40 repeats often function as assembly platforms for MULTIPROTEIN COMPLEXES.
Terms: WD40 Repeats Preferred Term
Term UI T000896334
Date03/02/2016
LexicalTag ABX
ThesaurusID NLM (2017); WD40 Motif
Term UI T000896338
Date03/02/2016
LexicalTag ABX
ThesaurusID NLM (2017); beta-Transducin Repeats
Term UI T000896337
Date03/02/2016
LexicalTag NON
ThesaurusID NLM (2017); WD40 Repeat
Term UI T000896335
Date03/02/2016
LexicalTag ABX
ThesaurusID NLM (2017); WD Repeats
Term UI T000896336
Date03/02/2016
LexicalTag ABX
ThesaurusID NLM (2017)

WD40 Repeats MeSH Descriptor Data 2023