Protein Domains MeSH Descriptor Data 2025

MeSH Heading: Protein Domains
Tree Number(s): G02.111.570.820.709.275.750; G02.111.570.820.709.610.500
Unique ID: D000072417
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000072417
Scope Note: Discrete protein structural units that may fold independently of the rest of the protein and have their own functions.
Entry Term(s): Peptide Domain; Protein Domain
Public MeSH Note: 2017; see PROTEIN STRUCTURE, TERTIARY 2000-2016
History Note: 2017; use PROTEIN STRUCTURE, TERTIARY 2000-2016
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/05/27

Allowable Qualifiers: drug effects (DE)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Chemical Phenomena [G02]
- Biochemical Phenomena [G02.111]
  - Molecular Structure [G02.111.570]
    - Molecular Conformation [G02.111.570.820]
      - Protein Conformation [G02.111.570.820.709]
        
        Protein Structural Elements [G02.111.570.820.709.275]
        
        Amino Acid Motifs [G02.111.570.820.709.275.500]
        
        Degrons [G02.111.570.820.709.275.625]
        
        Protein Domains [G02.111.570.820.709.275.750]
        
        C2 Domains [G02.111.570.820.709.275.750.125]
        
        Carbohydrate Binding Modules [G02.111.570.820.709.275.750.157]
        
        Catalytic Domain [G02.111.570.820.709.275.750.188]
        
        Discoidin Domain [G02.111.570.820.709.275.750.219]
        
        HMG-Box Domains [G02.111.570.820.709.275.750.235]
        
        Immunoglobulin Domains [G02.111.570.820.709.275.750.250]
        
        Kringles [G02.111.570.820.709.275.750.375]
        
        Methyl CpG Binding Domain [G02.111.570.820.709.275.750.438]
        
        Pleckstrin Homology Domains [G02.111.570.820.709.275.750.469]
        
        PR-SET Domains [G02.111.570.820.709.275.750.477]
        
        Proline-Rich Protein Domains [G02.111.570.820.709.275.750.485]
        
        Protein Interaction Domains and Motifs [G02.111.570.820.709.275.750.500]
        
        Repetitive Sequences, Amino Acid [G02.111.570.820.709.275.875]

Chemical Phenomena [G02]
- Biochemical Phenomena [G02.111]
  - Molecular Structure [G02.111.570]
    - Molecular Conformation [G02.111.570.820]
      - Protein Conformation [G02.111.570.820.709]
        
        Protein Structure, Tertiary [G02.111.570.820.709.610]
        
        Protein Domains [G02.111.570.820.709.610.500]

Protein Domains Preferred

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