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Methyl CpG Binding Domain MeSH Descriptor Data 2023


MeSH Heading
Methyl CpG Binding Domain
Tree Number(s)
G02.111.570.820.709.275.750.438
Unique ID
D000070593
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000070593
Scope Note
A protein domain of about 70 amino acids in length that folds into a sandwich structure consisting of a beta sheet, alpha helix, and C-terminal hairpin loop which forms a hydrophobic methylated-DNA binding patch. It binds to methylated CPG ISLANDS in eukaryotes and occurs with other DNA and CHROMATIN binding domains such as AT-HOOK MOTIFS in eukaryotic DNA BINDING PROTEINS.
Entry Term(s)
Methyl CpG DNA Binding Domain
Previous Indexing
DNA-Binding Proteins (1993-2016)
See Also
DNA Methylation
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/07/05
Methyl CpG Binding Domain Preferred
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