MeSH Browser

MeSH Heading: Ankyrin Repeat
Tree Number(s): G02.111.570.060.720.030; G02.111.570.820.709.275.500.030; G02.111.570.820.709.275.750.500.080; G02.111.570.820.709.275.875.030
Unique ID: D017089
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D017089
Scope Note: Protein motif that contains a 33-amino acid long sequence that often occurs in tandem arrays. This repeating sequence of 33-amino acids was discovered in ANKYRIN where it is involved in interaction with the anion exchanger (ANION EXCHANGE PROTEIN 1, ERYTHROCYTE). Ankyrin repeats cooperatively fold into domains that mediate molecular recognition via protein-protein interactions.
Entry Term(s): ANK Repeat; ANK Repeat Domains; Ankyrin Repeat Domains; Ankyrin Repeats; Ankyrin-Like Repeats
Previous Indexing: Amino Acid Sequence (1990-1992); Membrane Proteins (1990-1992)
Public MeSH Note: 93
History Note: 93
Date Established: 1993/01/01
Date of Entry: 1992/05/13
Revision Date: 2016/05/27

Allowable Qualifiers: drug effects (DE)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Chemical Phenomena [G02]
- Biochemical Phenomena [G02.111]
  - Molecular Structure [G02.111.570]
    - Amino Acid Sequence [G02.111.570.060]
      - Repetitive Sequences, Amino Acid [G02.111.570.060.720]
        
        Ankyrin Repeat [G02.111.570.060.720.030]
        
        Kelch Repeat [G02.111.570.060.720.273]
        
        Tetratricopeptide Repeat [G02.111.570.060.720.394]
        
        WD40 Repeats [G02.111.570.060.720.515]

Chemical Phenomena [G02]
- Biochemical Phenomena [G02.111]
  - Molecular Structure [G02.111.570]
    - Molecular Conformation [G02.111.570.820]
      - Protein Conformation [G02.111.570.820.709]
        
        Protein Structural Elements [G02.111.570.820.709.275]
        
        Amino Acid Motifs [G02.111.570.820.709.275.500]
        
        Ankyrin Repeat [G02.111.570.820.709.275.500.030]
        
        AT-Hook Motifs [G02.111.570.820.709.275.500.050]
        
        Cystine Knot Motifs [G02.111.570.820.709.275.500.127]
        
        F-Box Motifs [G02.111.570.820.709.275.500.205]
        
        Helix-Loop-Helix Motifs [G02.111.570.820.709.275.500.360]
        
        Immunoreceptor Tyrosine-Based Activation Motif [G02.111.570.820.709.275.500.440]
        
        Immunoreceptor Tyrosine-Based Inhibition Motif [G02.111.570.820.709.275.500.480]
        
        Kazal Motifs [G02.111.570.820.709.275.500.490]
        
        Kelch Repeat [G02.111.570.820.709.275.500.500]
        
        Leucine Zippers [G02.111.570.820.709.275.500.520]
        
        Poly-ADP-Ribose Binding Motif [G02.111.570.820.709.275.500.695]
        
        RNA-Binding Motifs [G02.111.570.820.709.275.500.869]
        
        Sterile Alpha Motif [G02.111.570.820.709.275.500.898]
        
        AAA Domain [G02.111.570.820.709.275.500.913]
        
        Tetratricopeptide Repeat [G02.111.570.820.709.275.500.920]
        
        WD40 Repeats [G02.111.570.820.709.275.500.927]
        
        Zinc Fingers [G02.111.570.820.709.275.500.985]

Chemical Phenomena [G02]
- Biochemical Phenomena [G02.111]
  - Molecular Structure [G02.111.570]
    - Molecular Conformation [G02.111.570.820]
      - Protein Conformation [G02.111.570.820.709]
        
        Protein Structural Elements [G02.111.570.820.709.275]
        
        Protein Domains [G02.111.570.820.709.275.750]
        
        Protein Interaction Domains and Motifs [G02.111.570.820.709.275.750.500]
        
        Ankyrin Repeat [G02.111.570.820.709.275.750.500.080]
        
        B30.2-SPRY Domain [G02.111.570.820.709.275.750.500.290]
        
        BTB-POZ Domain [G02.111.570.820.709.275.750.500.343]
        
        Death Domain Superfamily [G02.111.570.820.709.275.750.500.395]
        
        FERM Domains [G02.111.570.820.709.275.750.500.422]
        
        Kelch Repeat [G02.111.570.820.709.275.750.500.448]
        
        MYND Domains [G02.111.570.820.709.275.750.500.474]
        
        PDZ Domains [G02.111.570.820.709.275.750.500.500]
        
        RING Finger Domains [G02.111.570.820.709.275.750.500.625]
        
        src Homology Domains [G02.111.570.820.709.275.750.500.750]
        
        Sterile Alpha Motif [G02.111.570.820.709.275.750.500.813]
        
        Tetratricopeptide Repeat [G02.111.570.820.709.275.750.500.829]
        
        Tudor Domain [G02.111.570.820.709.275.750.500.844]
        
        WD40 Repeats [G02.111.570.820.709.275.750.500.875]
        
        WW Domains [G02.111.570.820.709.275.750.500.937]

Chemical Phenomena [G02]
- Biochemical Phenomena [G02.111]
  - Molecular Structure [G02.111.570]
    - Molecular Conformation [G02.111.570.820]
      - Protein Conformation [G02.111.570.820.709]
        
        Protein Structural Elements [G02.111.570.820.709.275]
        
        Repetitive Sequences, Amino Acid [G02.111.570.820.709.275.875]
        
        Ankyrin Repeat [G02.111.570.820.709.275.875.030]
        
        Kelch Repeat [G02.111.570.820.709.275.875.273]
        
        Tetratricopeptide Repeat [G02.111.570.820.709.275.875.394]
        
        WD40 Repeats [G02.111.570.820.709.275.875.515]

Ankyrin Repeat Preferred

Ankyrin-Like Repeats Related

ANK Repeat Domains Related

Ankyrin Repeat MeSH Descriptor Data 2025