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BTB-POZ Domain MeSH Descriptor Data 2022


MeSH Heading
BTB-POZ Domain
Tree Number(s)
G02.111.570.820.709.275.750.500.343
Unique ID
D000071757
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071757
Scope Note
A homodimerization protein interaction domain occurring at the N terminus of proteins that contain multiple copies of either CYS2-HIS2 ZINC FINGERS or KELCH REPEATS. It is characterized by a tightly intertwined dimer with an extensive hydrophobic interface. A surface-exposed groove lined with conserved amino acids is formed at the dimer interface, suggesting a peptide-binding site. Many BTB proteins are transcriptional regulators that are thought to regulate CHROMATIN structure.
Entry Term(s)
BTB (POZ) Domain
BTB Domain
Broad-Complex, Tramtrack and Bric a Brac Domain
POZ Domain
POxvirus and Zinc Finger Domain
Previous Indexing
Amino Acid Sequence (1994-2016)
DNA-Binding Proteins (1994-2016)
Protein Structure, Tertiary (1995-2016)
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/05/09
BTB-POZ Domain Preferred
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