MeSH Browser

MeSH Heading: CYS2-HIS2 Zinc Fingers
Tree Number(s): G02.111.570.820.709.275.500.985.250
Unique ID: D000070580
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000070580
Scope Note: A zinc finger motif of approximately 30 amino acids with the general sequence X2-Cys-X2,4-Cys-X12-His-X3,4,5-His that forms a simple beta sheet-beta sheet-alpha helix fold stabilized by zinc ions. It recognizes and binds to a variety of eukaryotic DNA sequences and is very common among sequence-specific DNA BINDING PROTEINS and TRANSCRIPTION FACTORS.
Entry Term(s): C2H2 Zinc Fingers; CYS2-HIS2 Zinc Finger Motifs; CYS2HIS2 Zinc Fingers
Previous Indexing: Amino Acid Sequence (1990-2016); Zinc Fingers (1991-2016)
Public MeSH Note: 2017
History Note: 2017
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/05/09

Allowable Qualifiers: drug effects (DE)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Concept UI: M000611017
Scope Note: A zinc finger motif of approximately 30 amino acids with the general sequence X2-Cys-X2,4-Cys-X12-His-X3,4,5-His that forms a simple beta sheet-beta sheet-alpha helix fold stabilized by zinc ions. It recognizes and binds to a variety of eukaryotic DNA sequences and is very common among sequence-specific DNA BINDING PROTEINS and TRANSCRIPTION FACTORS.
Terms: CYS2-HIS2 Zinc Fingers Preferred Term
Term UI T000888235
Date10/20/2015
LexicalTag ABX
ThesaurusID NLM (2017); CYS2HIS2 Zinc Fingers
Term UI T000888234
Date10/20/2015
LexicalTag ABX
ThesaurusID NLM (2017); CYS2-HIS2 Zinc Finger Motifs
Term UI T000888236
Date10/20/2015
LexicalTag ABX
ThesaurusID NLM (2017); C2H2 Zinc Fingers
Term UI T000888238
Date10/20/2015
LexicalTag ABX
ThesaurusID NLM (2017)

CYS2-HIS2 Zinc Fingers MeSH Descriptor Data 2025