NLM Logo

PHD Zinc Fingers MeSH Descriptor Data 2023

MeSH Heading
PHD Zinc Fingers
Tree Number(s)
Unique ID
RDF Unique Identifier
Scope Note
Zinc finger domains of approximately 50 to 80 amino acids in length that are characterized by a conserved Cysteine(3)-Histidine-Cysteine(4) amino acid motif which coordinates binding of two zinc ions. They are similar structurally to RING FINGER DOMAINS, with a globular fold topology of two BETA-SHEETS and an ALPHA-HELIX. PHD fingers occur in many proteins that function in chromatin-mediated gene expression and EPIGENETICS such as POLYCOMB-GROUP PROTEINS.
Entry Term(s)
PHD Domains
PHD Finger Domain
PHD Fingers
PHD Motif
PHD Motifs
PHD Zinc Finger
Previous Indexing
Amino Acid Sequence (1995-2017)
Molecular Sequence Data (1995-2017)
Public MeSH Note
History Note
Date Established
Date of Entry
Revision Date
PHD Zinc Fingers Preferred
page delivered in 0.142s