MeSH Browser

MeSH Heading: PDZ Domains
Tree Number(s): G02.111.570.820.709.275.750.500.500
Unique ID: D054731
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D054731
Scope Note: Protein interaction domains of about 70-90 amino acid residues, named after a common structure found in PSD-95, Discs Large, and Zona Occludens 1 proteins. PDZ domains are involved in the recruitment and interaction of proteins, and aid the formation of protein scaffolds and signaling networks. This is achieved by sequence-specific binding between a PDZ domain in one protein and a PDZ motif in another protein.
Entry Term(s): DHR Domains; DLG Homology Repeats Domains; GLGF Repeats Domains; PDZ Interaction Domains; PSD95-DLG-ZO1 Domains
Public MeSH Note: 2008
History Note: 2008
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2016/05/31

Allowable Qualifiers: drug effects (DE)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Concept UI: M0507255
Scope Note: Protein interaction domains of about 70-90 amino acid residues, named after a common structure found in PSD-95, Discs Large, and Zona Occludens 1 proteins. PDZ domains are involved in the recruitment and interaction of proteins, and aid the formation of protein scaffolds and signaling networks. This is achieved by sequence-specific binding between a PDZ domain in one protein and a PDZ motif in another protein.
Terms: PDZ Domains Preferred Term
Term UI T692730
Date03/02/2007
LexicalTag ACX
ThesaurusID NLM (2008); GLGF Repeats Domains
Term UI T692877
Date03/05/2007
LexicalTag ACX
ThesaurusID NLM (2008); DHR Domains
Term UI T692878
Date03/05/2007
LexicalTag ACX
ThesaurusID NLM (2008); PSD95-DLG-ZO1 Domains
Term UI T692879
Date03/05/2007
LexicalTag ACX
ThesaurusID NLM (2008); DLG Homology Repeats Domains
Term UI T692889
Date03/05/2007
LexicalTag ACX
ThesaurusID NLM (2008); PDZ Interaction Domains
Term UI T693126
Date03/07/2007
LexicalTag NON
ThesaurusID NLM (2008)

PDZ Domains MeSH Descriptor Data 2025