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Karyopherins MeSH Descriptor Data 2025


MeSH Heading
Karyopherins
Tree Number(s)
D12.776.157.530.750.500
D12.776.543.585.750.500
D12.776.660.502
Unique ID
D028884
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D028884
Scope Note
A family of proteins involved in NUCLEOCYTOPLASMIC TRANSPORT. Karyopherins are heteromeric molecules composed of two major types of components, ALPHA KARYOPHERINS and BETA KARYOPHERINS, that function together to transport molecules through the NUCLEAR PORE COMPLEX. Several other proteins such as RAN GTP BINDING PROTEIN and CELLULAR APOPTOSIS SUSCEPTIBILITY PROTEIN bind to karyopherins and participate in the transport process.
Entry Term(s)
Exportin
Exportins
Importin
Importins
Karyopherin
Transportin
Transportins
Registry Numbers
0
Previous Indexing
Nuclear Proteins (1995-2001)
Receptors, Cytoplasmic and Nuclear (1995-2001)
See Also
Active Transport, Cell Nucleus
Public MeSH Note
2002; IMPORTIN (now KARYOPHERINS) was indexed under NUCLEAR PROTEINS 1995-2001; TRANSPORTIN (now KARYOPHERINS) was indexed under NUCLEAR PROTEINS & RECEPTORS, CYTOPLASMIC AND NUCLEAR 1995-2001
History Note
2002; use KARYOPHERINS (NM) 1995-2001
Date Established
2002/01/01
Date of Entry
2001/07/25
Revision Date
2020/08/13
Karyopherins Preferred
Importins Narrower
Exportins Narrower
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