NLM Logo

beta Karyopherins MeSH Descriptor Data 2023


MeSH Heading
beta Karyopherins
Tree Number(s)
D12.776.157.530.750.500.249
D12.776.543.585.750.500.249
D12.776.660.502.500
Unique ID
D028961
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D028961
Scope Note
Nucleocytoplasmic transport molecules that bind to ALPHA KARYOPHERINS in the CYTOSOL and are involved in transport of molecules through the NUCLEAR PORE COMPLEX. Once inside the CELL NUCLEUS beta karyopherins interact with RAN GTP-BINDING PROTEIN and dissociate from alpha karyopherins. Beta karyopherins bound to RAN GTP-BINDING PROTEIN are then re-transported to the cytoplasm where hydrolysis of the GTP of RAN GTP-BINDING PROTEIN causes release of karyopherin beta.
Entry Term(s)
Importin-beta
Kap95 protein
Karyopherin beta
Karyopherin-beta
Karyopherin-beta Subunit
beta Importins
p92 nuclear protein
Registry Number
0
Previous Indexing
Nuclear Proteins (1995-2001)
Public MeSH Note
2002; KARYOPHERIN BETA & IMPORTIN-BETA were indexed under NUCLEAR PROTEINS 1995-2001
History Note
2002; use BETA KARYOPHERINS (NM) 1995-2001; for IMPORTIN-BETA use KARYOPHERINS (NM) 1995-2001
Date Established
2002/01/01
Date of Entry
2001/07/25
Revision Date
2005/06/30
beta Karyopherins Preferred
page delivered in 0.154s