- Concept UI
- M000599991
- Registry Numbers
- 0
- Scope Note
- A family of predominantly nuclear proteins that regulate gene transcription and protein degradation. The expansion of CAG trinucleotide repeats in genes that encode Ataxins is associated with SPINOCEREBELLAR ATAXIAS (SCA). In SCA patients, the number of CAG repeats correlates with the severity of disease and inversely correlates with the age of disease onset.
- Terms
-
Ataxins
Preferred Term
Term UI
T000871238
Date11/25/2014
LexicalTag
NON
ThesaurusID
NLM (2016)
-
Ataxin
Term UI
T000998068
Date11/20/2019
LexicalTag
NON
ThesaurusID
NLM (2021)
-
Ataxin Protein
Term UI
T000998069
Date11/20/2019
LexicalTag
NON
ThesaurusID
NLM (2021)
-
Spinocerebellar Ataxia Protein
Term UI
T000998070
Date11/20/2019
LexicalTag
NON
ThesaurusID
NLM (2021)
-
Ataxin Proteins
Term UI
T000872147
Date12/15/2014
LexicalTag
NON
ThesaurusID
NLM (2016)
-
Spinocerebellar Ataxia Proteins
Term UI
T000874561
Date02/02/2015
LexicalTag
NON
ThesaurusID
NLM (2016)