MeSH Browser

MeSH Heading: S100 Proteins
Tree Number(s): D12.776.157.125.750; D12.776.631.658
Unique ID: D009418
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D009418
Scope Note: A family of highly acidic calcium-binding proteins found in large concentration in the brain and believed to be glial in origin. They are also found in other organs in the body. They have in common the EF-hand motif (EF HAND MOTIFS) found on a number of calcium binding proteins. The name of this family derives from the property of being soluble in a 100% saturated ammonium sulfate solution.
Entry Term(s): Antigen S 100; Nerve Tissue Protein S 100; S-100 Protein; S100 Protein; S100 Protein Family
Previous Indexing: Nerve Tissue Proteins (1966-1972)
Public MeSH Note: 2003; see NERVE TISSUE PROTEIN S 100 1984-2002, see NERVE TISSUE PROTEINS 1975-1983
History Note: 2003(1973)
Date Established: 1984/01/01
Date of Entry: 1999/01/01
Revision Date: 2023/06/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0014662
Scope Note: A family of highly acidic calcium-binding proteins found in large concentration in the brain and believed to be glial in origin. They are also found in other organs in the body. They have in common the EF-hand motif (EF HAND MOTIFS) found on a number of calcium binding proteins. The name of this family derives from the property of being soluble in a 100% saturated ammonium sulfate solution.
Terms: S100 Proteins Preferred Term
Term UI T491045
Date04/25/2002
LexicalTag ACX
ThesaurusID NLM (2003); S100 Protein
Term UI T001004697
Date01/06/2020
LexicalTag NON
ThesaurusID NLM (2021); Antigen S 100
Term UI T028085
Date11/28/1977
LexicalTag ACX
ThesaurusID UNK (19XX); Nerve Tissue Protein S 100
Term UI T028086
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1973); S-100 Protein
Term UI T028087
Date07/30/1980
LexicalTag ACX
ThesaurusID UNK (19XX); S100 Protein Family
Term UI T491044
Date04/25/2002
LexicalTag ACX
ThesaurusID NLM (2003)

S100 Proteins MeSH Descriptor Data 2025